Acute and Recurrent Thromboembolic Disease

Pulmonary thromboembolic disease. Clinical management of acute and chronic disease.

Pulmonary thromboembolism falls between the areas of pulmonology and cardiology, internal medicine and intensive care, radiology and nuclear medicine, and hematology and cardiothoracic surgery. Depending on their clinical background, physicians faced with a patient with a pulmonary thromboembolism may speak different languages and adopt different treatment approaches. Now, however, there is an ...

Obesity and thromboembolic disease.

Various abnormalities of hemostasis have been described in obesity, mainly concerning increased levels of plasminogen activator inhibitor-1, but other abnormalities of coagulation and platelet activation have been reported as well. Circulating microparticles have also been observed in obese patients. These suggest that obesity would be a risk factor for venous thromboembolism (VTE). Analysis of...

Acute Thromboembolic Pulmonary Hypertension

Acute pulmonary thromboembolism is a common and life-threatening condition that requires prompt evaluation and management to improve outcomes. In severe cases, acute pulmonary thromboembolism causes a rapid rise in pulmonary pressures precipitating compromised right ventricular (RV) function. Acute elevation in pulmonary pressures with RV failure is associated with poor outcome. When pulmonary ...

Oral contraceptives and thromboembolic disease.

Venous thromboembolic disease and pregnancy.

From the Division of Pulmonary and Critical Care Medicine (P.E.M.), the Department of Obstetrics and Gynecology (L.A.P.), and the Department of Anesthesiology (L.A.P.), Thomas Jefferson University, Philadelphia. Address reprint requests to Dr. Marik at Pulmonary and Critical Care Medicine, Thomas Jefferson University, 834 Walnut St., Suite 650, Philadelphia, PA, 19107, or at paul.marik@ jeffers...